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Hydropic gallbladder

  1. Gastroepato
  2. Gastroenterology
  3. Hydropic gallbladder
  4. Gallbladder, news

When a stone stops in the cystic duct (for example during a colic caused by a biliary calculus), this can cause difficulty in biliary outflow and, eventually, complete obstruction. Retention can cause an obstacle to the outflow of bile that is known as bile duct hydrops. The hydrops begins with the symptoms of local inflammation. It is a complication of cholelithiasis, due to the exclusion of the gallbladder from the biliary circulation, due to a blockage of the cystic duct or of the neck of the gallbladder itself by a biliary calculus. The mucosa of the gallbladder absorbs the bile pigments and other components of the bile secreting mucus; the cavity is thus filled with a mucoid solution and increases in size. This condition can be further complicated, in the case of superinfection, with an empyema, or it can undergo perforation. More rarely a gallbladder infarction can occur.

1.surgical intervention of removal of hydropic
gallbladder in laparoscopy.
2. CT, documents hydropic cholecyst, arrows

Diagnosis

In clinically more evident cases, a tense and elastic gallbladder can be palpated under the costal arch, which, in cases of pure hydrops, is not particularly painful to pressure. Ultrasound is evident in an enlarged gallbladder without signs of inflammation. Depending on the position, the calculations can be easily identified, but if they are located exclusively in the cystic duct, their identification may be a little more difficult. Also CT is indicated in study.


Therapy and prognosis

Hydrops can cause scar wounds on the gallbladder wall with calcium deposits ("porcelain gallbladder"). To avoid further complications it is necessary to perform a cholecystectomy in the interval between one colonic and another. The superinfection of the bile that leads to a cholecyst empyema is particularly dangerous. Therefore, when diagnosing a case of hydrops of the gallbladder it is necessary to intervene urgently by subjecting the patient to surgery because an increase in the clinical picture could even cause a risk for the patient's life.


Gallblad empyema

By empyema of the gallbladder we mean the bacterial infection of the contents of a previously hydropic gallbladder. In this process the gallbladder ends up being filled with pus. In this situation there is a risk of perforation resulting in extremely severe purulent peritonitis, followed by sepsis and shock. As in the case of cholecystitis and cholangitis, the possible microorganisms start from the intestinal tract. The most frequent are the E. coli, enterococci, Klebsiella, clostridia and enterobacteria in general.

Clinic and diagnosis

Clinically an empyema of the gallbladder manifests itself with significant pain in the right hypochondrium, both spontaneous and pressure, and abdominal tension. Patients are very suffering and have high fever. On ultrasound, the gallbladder empyema distinguishes itself from a simple hydrops due to its corpuscle content and thickened walls. Laboratory analyzes indicate intense inflammation, with neutrophilic leukocytosis that almost always exceeds 20,000 elements / u.L.

Bottom of the hydropic gallbladder, in the center, with omental bridles adhered to the bottom and body of the gallbladder, such as a red onion, at the top  the liver, of chocolate brown color.

Therapy

The therapy of the gallbladder empyema consists in the use of broad-spectrum antibiotics and in the immediate surgical removal of the gallbladder. In these cases a laparoscopic cholecystectomy can not be considered, unlike what happens in an elective removal of the gallbladder. In fact, in order to ascertain with certainty whether a perforation or penetration into adjacent organs is produced, a wide opening of the dome is required; in other words it is essential to realize a cholecystectomy with a conventional approach. It is also mandatory to prolong the post-surgical antibiotic treatment for a period of 10-14 days.

Complications

Since the common bile duct and the Wirsung pancreatic duct, in 80% of cases, have a common outlet, when a calculation obstructs the distal portion of the common duct, in addition to cholestasis an obstacle to the drainage of pancreatic juices is produced, with the result to have acute pancreatitis. This causes a retention that affects the pancreatic parenchyma and which, in the long run, causes acute pancreatitis. Another associated pathological condition may consist of a cholangitis, with infection and the recovery of germs in the biliary tract. Finally, for purulent exudate from the walls of the gallbladder you can have first a "platoon" for intervention of the topic and subsequently adherences between omentum and gallbladder.

Diagnosis and treatment

In all cases of acute pancreatitis, it must be discarded with absolute certainty, performing an ultrasound, that biliary lithiasis is present; in case of doubt an endoscopic retrograde cholangiography (ERCP) should be performed. If possible, you will have to extract the calculation that causes the obstruction endoscopically.

Prognosis

Once the calculation is extracted, the clinical picture usually improves rapidly, especially the epigastric pain. At the same time, laboratory values ​​must regress towards normal in the first 24 hours after surgery. In any case, it must be taken into account that ERCP can cause pancreatitis due to the mechanical manipulation of the duodenal papilla and the diffusion of the contrast medium into the pancreatic duct.

Gastroenterology