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The patient with a dry, productive cough

  1. Gastroepato
  2. Pneumology
  3. The patient with a dry, productive cough
  4. Respiration and respiratory failure
  5. Respiratory system
  6. Heart failure
  7. The respiratory patient
  8. Respiratory distress syndrome
  9. The dyspnoic patient
 

Definition and pathogenesis

Definition: the cough is a violent  process of breathing out, like an "explosive expiration", often to allow the drainage outside of foreign bodies (the mouthful that goes in trachea it's a classic example of explosive cough) or any secretions, for example the smoker's catarrh (smoking).
It is one of the most common causes for which the doctor is asked.
The causes of cough are the most disparate; it can be the coughing in the decubitus of the first hours by night , due to congestion of the lung that manifests itself in the diseased heart patient, where lung is not aspirated by the weakened heart and therefore it's congested, a condition that causes cough; or it is the cough of the chronic bronchopathic smoker, of the asthmatic patient, accompanied by wheezing, the cough of the acute bronchitis.

Still we distinguish a subtle and persistent cough of the patient with lung tumor and with pleural effusion.

We distinguish a cough:
Acute and subacute
Persistent
Chronic

Acute cough, in acute infections, which lasts for up to 3 weeks, becomes subacute, if it lasts less than 3 weeks and up to eight weeks; persistent, which to be defined as such must last for at least two weeks. Chronic cough is characteristic of chronic obstructive bronchopathy.
The cough can be voluntary or reflected and as such it needs an afferent way, that is a road that leads the signal towards the center, then the central nervous system, and an efferent way, that is, which brings the result of the afference and, therefore, the action of cough itself.
The afferent pathway includes signal receptors which are the terminations of the sensitive trigeminal,  superior glossopharyngeal and vague; the efferent pathway instead follows the recurrent laryngeal nerve, responsible for the closure of the glottis and of the spinal nerves (which cause the contraction of the muscles of the abdominal and thoracic wall.
After a suitable stimulus, for example of the powder to which a patient can be allergic, begins a deep inhalation followed by the closing of the glottis, the release of the diaphragm and finally the contraction of the muscles of the abdominal and thoracic wall which occurs at a closed glottis; then the air is expelled violently and with the air jet even the secretions of mucus are removed out..

Causes of cough

Foreign substances, powders, smoke, vapors
Foreign bodies
Irritation of the respiratory tract and secretions
Esophageal reflux with aspiration of liquid into the trachea
Drugs for example ace-inhibitors (eg enalapril and similar molecules) related to the accumulation of bradykinin or substance P, by inhibition of the conversion enzyme that degrades these substances.
Inflammation of the respiratory mucosa,
Bronchoconstriction (asthma)
Conditions of edema and pulmonary preedema (!)
Heart failure
Pertussis, that is, bordetella pertussis infection
Chronic hostile bronchitis
Attack of bronchial asthma
Lung cancer (bronchial carcinoma or carcinoid)

How to visit the patient with a cough?

The anamnesis, that is the history of the patient must be indagated

Is the cough acute or chronic? Is there a possible respiratory infection, is there a fever? Is it seasonal cough, for example in spring?

Do you associate with respiratory distress?

 Is there sputum? And is the sputum streaked with blood?

 Does the patient smoke? Does your patient work  in industries ? Does he live at home, in dusty places, eg libraries, archives, law firms with masses of parchment practices?

 Does he use enapren, enalapril, other ace inhibitors?

Does he suffer from heart and have swollen feet (see special heart failure)? Does he have dyspnoea? Does he have heart failure?

Cf  Respiratory sounds

How to do the objective exam?

It can highlight signs of extrapulmonary cough causes, such as:
Heart failure, with congestion of the pulmonary circulation; in these cases the patient is usually elderly and at the auscultation of the chest, the signs of the congestion of the pulmonary circuit appear, like the crackles, which are the signs of the condition of pulmonary edema or the find of a  "wet lung", badly aspirated by a weak  heart, and limited gas exchanges are found at hemogas analysis..
 
Sometimes at the nose inspection a chronic rhinitis with flat and fibrous nasal  mucosa and rhinorrhea, or a cobbled mucosa or a pharyngeal hyperemia or pus plaques to the tonsils that document infections; to the auscultation of the inspiratory crackles that orientate the diagnosis to an interstitial lung diseases;

the chest x-ray may suggest the cause of the cough, due to the presence of pleuroparenchymal lesions or simply to the accumulation of the vascular circulation or the opaque masses, the nodules, the pulmonary thickening, blurred, or to net margins, or lobates, or whole lungs that appear to be affected by inflammatory processes, lobar pneumonias, interstitiopathies, "honeycomb" appearance, etc.
So the old chest-X-ray always has the right weight in the patient's control. It must follow, if appropriate, the tests of respiratory function or spirometry, especially in the bronchitic patient.
With spirometry we can highlight FEV 1, which is the air flow measured in volume at the first second of expiration, expression of obstruction of the upper airways, or bronchoconstriction which in the most stubborn cases is manifested by the "dry" hissing noise or bronchostenosis serrata.

If sputum is present, it should be inspected and ruled out that there may be blood traces, expression of respiratory tract injury, or on an inflammatory basis, or on a dysplastic basis, as for tumors, or on an infectious basis, as was the case for tuberculosis .
If there is a yellow-foamy sputum, diagnosis is oriented towards thepurulent respiratory forms, in general, of chronic bronchitic smokers, bronchiectasis and pneumonia with lung abscess.

Examination that must follow these will be the sputum culture and the fresh examination with research of resistant alcohol-acid bacterium or Koch's bacillus.
When the blood is more abundant we speak of hemoptysis, that is "aima ptiuo", from the Greek language, a sputum with  blood, and refers to the emission of blood from the respiratory tract.
Bronchoscopy is a technique to be performed to visualize the respiratory pathways and to exclude injuries, better if associated with BAL, that is to wash the respiratory tract with the study of the washing or brushing liquid, ie brushing of the suspected lesions and epithelia.
Upon inspection of the bronchus, granulomas can be detected, which often occurs in sarcoidosis. The tac with contrast or without suggesting the neoplastic nature of the lesions or rather a simple interstitiopathy.

Cough treatment

It's not good to entrust your health to the first employee of the pharmacy who sells you a cough medicine, which often only causes damage to your money and your health.!
 

The drugs used for coughing are:
The sedative drugs, which, personally I use in rare cases, for example if there are costal fractures, aren't indicated. The only indications are in the rib fractures,  because  the fractures can tearing the lung if a patient has cough attacks. Sedatives are extracts of opium, opioids, or opiates, e.g. dextromethorphan and codeine, which are sometimes sold as counter products.
Corticosteroids, methylpredinisolone, beclometasone, fluticasone, etc., are the right indication drugs used in chronic bronchitis. or the hypatropium bromide that sedates the afferent way in the reflex of the cough; antibiotics  which are generally cephalosporins and macrolides or simply amoxicillin, in the more severe cases also piperacillin and tazobactam).
Fluidizers, excellent drugs to thin and promote the expulsion of mucus, but dangerous in the bronchopathic patient or in a patient affected by heart disease, where they can have very unpleasant side effects because the mucus is dissolved but often can not be expectorated due to lack of energy and the patient has no a benefit but rather he suffocates.
Diuretics that are used in conditions of heart failure and lung edema, to "discharge" the small pulmonary circulation, so to speak! In the most severe cases we also use nitroderivatives that can be administered in a vein in urgencies eg. nitroglycerin in the attack of pulmonary edema, to reduce the resistance of the lung.
Beta 2 stimulants for aerosols, fast-acting ones (eg salbutamol, the old ventolin spray) and long-acting beta 2, formeterol, are indicated in chronic bronchitic cough; not to be neglected the action of intravenous theophylline administered in the patient with bronchostenosis;
The adrenaline that I personally see used for aerosol or under diluted skin in the unresolvable asthma accesses for close bronchostosis

Lastly or primarily the God's intervention that you must always pray when you are treating an asthmatic patient with a  serious broncostenosis! And I know something about it!
In the very last you must remind to your women, that a super-clean and dust-free house, with dry and stale air, when the child is kept inside, covered with sweaters, is more exposed to asthmatic bronchitis than any other child in the third world!
Let them live their lives in peace and "when the wind of life blows", let them raise their sails "(Spoon River).
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